In practice there’s no reason to suspect that any particular piece of information is inadequate before it is revealed to be otherwise. But in theory there’s no reason to exclude anything from suspicion. It is characteristic of all interpretations, meanings, and values that they are never the last word. They are all potentially obsolete. Reality is not just occasionally precarious – it has no permanent foundations whatsoever. It is the nature of knowledge to be fragmentary and partial. This is the first and final, the ultimate source of anxiety.